Monilethrix is a rare hair condition, and we will whip, flip and understand this rare condition in this article. Monilethrix is a rare inherited disorder characterized by sparse, dry, and/or brittle hair that frequently breaks before achieving more than a few inches in length. The hair may also be lackluster, and there can be patchy areas of hair loss (alopecia). Another common symptom may be the appearance of elevated spots (papules) surrounding the hair follicles that may be blanketed with gray or brown crusts or scales (perifollicular hyperkeratosis). The hair shaft resembles a string of evenly-spaced beads when it is viewed under a microscope.
In most cases, this hair condition is inherited as an autosomal dominant trait. Monilethrix is due to mutations by one of several genes. Mutations withinside the KRT81 gene, the KRT83 gene, the KRT86 gene, or the DSG4 gene account for maximum instances of monilethrix. These genes provide commands for making proteins that provide structure and energy to strands of hair.
In most cases of monilethrix, the hair is normal at birth. It can then be slowly changed through unusual hair during the first few months to 2 years of life. In a few uncommon instances, the hair can be abnormal at birth (congenital). Scalp hair is most often affected by monilethrix. The entire scalp or small areas of the scalp can be involved. In a few cases, eyelashes, eyebrows, pubic hair, and/or different body hair can also be affected. In addition, the patchy loss of hair (alopecia) is a common feature of this disorder. Progressive hair loss might also additionally result in scattered bald patches or baldness.
The diagnosis of monilethrix can be shown through an intensive medical assessment and microscopic examination of the hair. There is no precise treatment that exists for monilethrix. Spontaneous resolution following puberty has happened in a few cases. In affected females, the condition improves throughout pregnancy. Genetic counseling might be of advantage for affected people and their families. Other forms of treatments are symptomatic and supportive therapies. If you suspect this to have in your family, better seek medical check up for proper identification of the underlying cause of the hair condition.
NO I Zamubec Alomar C. Adlawan, RND
References:
- Monilethrix- General Discussion
https://rarediseases.org/rare-diseases/monilethrix/
- Causes
