A healthy adult will urinate between 1 and 3 quarts (946.4 milliliters to 2.84 liters) of urine per day, according to the National Institute of Diabetes and Digestive and Kidney Diseases. Diabetes insipidus patients can produce up to 20 quarts (18.9 liters) of urine per day. The Cleveland Clinic defines diabetes insipidus as a rare condition characterized by a problem with antidiuretic hormone secretion. Because of their inability to control the amount of water in their urine, patients with diabetes insipidus have a lot of diluted (clear) urine.
Cindie Slightham of Healthline stated that Diabetes insipidus is unrelated to diabetes mellitus (frequently known as diabetes) and has no effect on blood sugar levels. This means that diabetes insipidus can exist without diabetes. Diabetes insipidus can strike anyone at any time. The word "insipid" means "flavorless," and clear, odorless urine is a common symptom of diabetes insipidus. The majority of cases of diabetes insipidus are caused by a lack of ADH or a poor response to ADH by the kidneys. When the body is dehydrated or has low blood pressure, it produces more ADH. The increase in ADH instructs the kidneys to retain more water rather than releasing it through urine. Central diabetes insipidus, nephrogenic diabetes insipidus, dipsogenic diabetes insipidus, and gestational diabetes insipidus are the four types of diabetes insipidus, according to Cindie Slightham.
What medical issues are linked to diabetes insipidus? Most people urinate one to two liters of urine per day, according to the Cleveland Clinic, but a person with diabetes insipidus may urinate three liters or more. Patients frequently need to urinate in the middle of the night. These patients are at risk of dehydration because they are losing so much water in their urine. Patients with diabetes insipidus experience increased thirst and drink a lot of water. If a patient does not have access to drinking water, he or she cannot compensate for the loss of water, and the chemicals in the body become "concentrated," resulting in elevated sodium levels in the blood (hypernatremia).
According to the Mayo Clinic, a water deprivation test is used to diagnose diabetes insipidus, in which a patient is monitored by a doctor and a health care team and asked to stop drinking fluids for several hours. ADH allows your kidneys to reduce the amount of fluid lost in the urine, preventing dehydration while fluids are restricted. A magnetic resonance imaging (MRI) scan can detect abnormalities in or near the pituitary gland. This is a non-invasive test. It creates detailed images of brain tissues using a powerful magnetic field and radio waves. Your doctor may recommend genetic testing if other members of your family have had problems with excessive urination. The type of diabetes insipidus you have and the severity of your condition will determine your treatment options. In minor cases, your doctor may simply suggest that you drink more water.
Cindie Slightham also emphasized the importance of lifestyle changes in the treatment of diabetes insipidus. Avoiding dehydration is the most important action. You can do this by carrying water with you wherever you go or offering water to your child with diabetes insipidus every few hours. Your doctor will assist you in determining the amount of fluid you should drink each day. Your prognosis is determined by the cause of your diabetes insipidus. When diabetes insipidus is properly managed, the condition rarely leads to serious or long-term complications.
PNFP Marie-Claire Gaas, RND
References:
- Everything You Should Know About Diabetes Insipidus (DI)
Medically reviewed by Kelly Wood, MD — Written by Cindie Slightham — Updated on February 14, 2022
https://www.healthline.com/health/type-2-diabetes/diabetes-insipidus
- Diabetes Insipidus
https://my.clevelandclinic.org/health/diseases/16618-diabetes-insipidus
- Diabetes Insipidus
National Institute of Diabetes and Digestive and Kidney Diseases
https://www.niddk.nih.gov/health-information/kidney-disease/diabetes-insipidus
- Diabetes insipidus
https://www.mayoclinic.org/diseases-conditions/diabetes-insipidus/diagnosis-treatment/drc-20351274